Which symptom is commonly seen in early alcohol withdrawal?

• A. Tremors
• B. Delirium tremens
• C. Autonomic instability
• D. Seizures

Answer: (D)

When someone stops drinking after regular, long-term use, the brain shifts from a depressant state to a rebound hyperexcitable one. The body’s adaptation to alcohol involves reduced inhibitory GABA activity and increased excitatory glutamate activity. Once alcohol is removed, this imbalance can lead to seizures as an early and notable manifestation of withdrawal. These convulsions often appear within the first day or two and signal a need for prompt medical care, because they can escalate or lead to other serious complications if not treated. Tremors and autonomic instability can also occur early, but seizures stand out as a key early withdrawal complication that highlights the risk and urgency of management.